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Concussions in NFL Players Could be Linked to Sexual Problems Later in Life

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Concussions in NFL Players Could be Linked to Sexual Problems Later in Life A history of concussion might influence sexual function later in life, according to a recent study of professional football players.

A concussion is a type of traumatic brain injury sustained during a forceful blow to the head. Symptoms may include headache, nausea, confusion, dizziness, disorientation, and memory problems. Some people with concussions lose consciousness.

The researchers surveyed 3,506 men who had played American-style football for the National Football League (NFL) after 1960. (After that date, most players wore hard plastic helmets.) The respondents ranged in age from 24 to 89 years, with an average age of 52. They had played for an average of 7 seasons.

The men reported on concussion symptoms experienced while practicing or playing football. They also told researchers whether a doctor had ever suggested treatment or prescribed medication for ED or testosterone deficiency.

Testosterone is an important hormone for men’s sexual function. When men have low levels of testosterone, they might become less interested in sex and have difficulty getting erections.

ED was a problem for almost 23 percent of the men, and about half of them took medication for it.

About 18% of the respondents said they had low testosterone, and about 40% took medication.

 

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Men's Sex

Birth Control Pills for Men are Possible, Studies Suggest

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Birth Control Pills for Men are Possible, Studies SuggestBirth control pills may eventually be available for men, scientists say.

A final product may still be years in the making, but researchers have deemed the medications safe and tolerable for healthy men.

The results of one study were presented at the annual meeting of the Endocrine Society in March 2019.

The drug, 11-beta-MNTDC, may reduce the production of sperm without decreasing a man’s libido. The drug behaves like testosterone, the hormone that drives sexual desire and gives men some of their masculine characteristics. But it does not trigger sperm production in the testes.

Forty healthy men participated in the 28-day study. Each day, 14 men took 200 mg of the 11-beta-MNTDC drug, and 16 men took 400 mg. The remaining 10 men took a placebo pill.

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Peyronie’s Disease: More Men Receiving CCH Injections

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Peyronie’s Disease: More Men Receiving CCH Injections Nowadays, more men with Peyronie’s disease are being treated with injections of collagenase clostridium histolyticum (CCH) than surgery, according to recent research.

Peyronie’s disease is characterized by plaques of hardened scar tissue that form on the penis, just below the skin’s surface. The plaques make the penis lose some of its flexibility. As a result, the penis starts to bend. Sometimes, the curve is so severe that intercourse is difficult. Men with Peyronie’s disease may also experience pain and erectile dysfunction (ED).

Surgery to correct the curve is a common treatment. CCH injections, which are targeted directly at the plaques, were approved in 2014.

The study findings are based on insurance claims data for 36,156 men who were first diagnosed with Peyronie’s disease between 2011 and 2017. Diagnosis rates did not change much during that period.

In 2014, the treatment rate with either CCH or surgery was 9.8%, but the rate rose to 15.5% by 2017, reflecting an increase in men undergoing CCH injections. After CCH injections were approved, their use as a first-line treatment increased an average of 1.6% per year.

The ratio of CCH to surgery as a first-line treatment increased from 1:1 in 2014 to about 2:1 by 2017.

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Low Testosterone Common in Germ Cell Tumor Survivors

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Low Testosterone Common in Germ Cell Tumor SurvivorsIn a recent study of germ cell tumor survivors, roughly half had hypogonadism – low testosterone – regardless of whether they were treated with surgery alone or surgery with platinum-based chemotherapy, scientists report in the journal Supportive Care in Cancer.

However, patients who had chemotherapy added to their surgical treatment were more likely to have male aging symptoms.

Germ cells are reproductive cells: egg cells in females and sperm cells in males. Tumors form when these cells grow and accumulate in an abnormal way. Some germ cell tumors are cancerous. When they are, they usually develop into ovarian cancer or testicular cancer.

The study included 199 germ cell tumor survivors between the ages of 18 and 50. Each participant completed a quality of life questionnaire at the start of the study and again three and six months later.

About 48% of the entire group had low testosterone. (For this study, hypogonadism was diagnosed if a man’s testosterone levels were below 300 ng/dL.)

Next, the researchers looked at testosterone levels based on type of treatment. Among patients who had had both surgery and chemotherapy, the low testosterone rate was 51%. For those who had surgery alone, the rate was 45%.

Patients who had low testosterone levels were more likely to have reported fatigue, poor sleep quality, and worse general health at the start of the study.

When the scientists compared quality of life assessment scores for the two groups, they found no statistically significant differences. However, those who had had both surgery and chemotherapy “exhibited more symptoms related to male aging.”

Resources

Mayo Clinic

“Germ cell tumors”

(May 25, 2019)

https://www.mayoclinic.org/diseases-conditions/germ-cell-tumors/symptoms-causes/syc-20352493

Oncology Learning Network

Porcelli, Hina

“Surgery With or Without Chemo Yields Low Testosterone in GCT Survivors”

https://www.oncnet.com/news/surgery-or-without-chemo-yields-low-testosterone-gct-survivors

Ovarian Cancer Research Alliance

“Chemotherapy”

https://ocrahope.org/patients/about-ovarian-cancer/treatment/chemotherapy/

Supportive Care in Cancer

Khanal, N., et al.

“The effects of hypogonadism on quality of life in survivors of germ cell tumors treated with surgery alone versus surgery plus platinum-based chemotherapy”

(Abstract. Published: November 9, 2019)

https://link.springer.com/article/10.1007/s00520-019-05117-0

WebMD

“What Are Germ Cell Tumors?”

(Reviewed: October 12, 2019)

https://www.webmd.com/cancer/germ-cell-tumors#1

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